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CDSCO & WHO Model Essential Medicines Formulary

Medicines & Drug Database A–Z

Search over 13 educational drug references. Access indications, general usage notes, precautions, and interaction warnings.

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Penicillin AntibioticRx

Amoxicillin

Generic: Amoxicillin

Treat bacterial infections

⚙️ Work Mechanism:

Amoxicillin destroys bacteria by sabotaging their ability to construct protective cell walls. As bacteria divide, their cell walls weaken and pop under fluid pressure, curing the bacterial infection.

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Antibiotic (Penicillin + Beta-Lactamase Inhibitor)Prescription

Amoxicillin and Potassium Clavulanate

Generic: Amoxicillin Trihydrate and Potassium Clavulanate

Indicated for severe or recurrent acute otitis media, acute bacterial sinusitis, community-acquired pneumonia, acute exacerbations of chronic bronchitis, uncomplicated and complicated urinary tract infections (pyelonephritis, recurrent cystitis), skin and soft-tissue infections (cellulitis, animal bites, severe dental abscesses), and intra-abdominal or pelvic infections.

⚙️ Work Mechanism:

This medicine combines two active agents that work together as a powerful antibacterial team: Amoxicillin attacks and breaks down the bacterial cell wall, causing bacteria to rupture and die. Potassium Clavulanate acts as an enzyme shield, disarming the chemical weapons (beta-lactamase enzymes) that resistant bacteria produce to destroy antibiotics. By neutralizing bacterial resistance, the combination cures deep and persistent infections.

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Macrolide AntibioticRx

Azithromycin

Generic: Azithromycin

Treat bacterial infections

⚙️ Work Mechanism:

Azithromycin stops bacteria from growing and multiplying by jamming their protein-building machinery. Without essential proteins, bacteria cannot survive.

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Antibiotic (3rd Gen Cephalosporin)Prescription

Cefpodoxime Proxetil

Generic: Cefpodoxime Proxetil

Indicated for acute community-acquired pneumonia (CAP), acute bacterial exacerbations of chronic bronchitis (AECB), acute maxillary sinusitis, acute otitis media, streptococcal pharyngitis/tonsillitis, uncomplicated skin and soft tissue infections, and uncomplicated urinary tract infections (acute cystitis and uncomplicated gonococcal urethritis).

⚙️ Work Mechanism:

Cefpodoxime is a third-generation cephalosporin antibiotic that kills bacteria by preventing them from building their protective cell walls. By inactivating bacterial penicillin-binding proteins (PBPs), it causes the bacterial wall to crack, leak, and burst under internal osmotic pressure, rapidly clearing bacterial infections of the chest, throat, ears, sinuses, and urinary tract.

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Antibiotic (2nd Gen Cephalosporin)Prescription

Cefuroxime Axetil

Generic: Cefuroxime Axetil

Indicated for acute bacterial maxillary sinusitis, acute otitis media, pharyngitis/tonsillitis, acute bacterial exacerbations of chronic bronchitis, secondary bacterial infections of acute bronchitis, uncomplicated skin and skin-structure infections, uncomplicated urinary tract infections, and early Lyme disease (erythema migrans).

⚙️ Work Mechanism:

Cefuroxime is a second-generation antibiotic that destroys bacteria by breaking down their protective cell wall. It binds to essential bacterial enzymes (penicillin-binding proteins) that lock cell wall components together. Without this protective barrier, bacteria cannot survive and rupture, eradicating stubborn lung, sinus, ear, and Lyme disease infections.

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Antibiotic (1st Gen Cephalosporin)Prescription

Cephalexin

Generic: Cephalexin (Cefalexin)

First-line therapy for skin and soft tissue infections (cellulitis, impetigo, folliculitis, furuncles, wound infections), streptococcal pharyngitis/tonsillitis, uncomplicated urinary tract infections (acute cystitis), acute otitis media, and bone infections (osteomyelitis) caused by susceptible organisms.

⚙️ Work Mechanism:

Cephalexin works by disabling the enzymes bacteria need to build and maintain their strong cellular outer walls. As the bacteria attempt to grow and divide without intact peptidoglycan mesh, their cell wall breaks down and bursts due to internal fluid pressure, killing the bacteria and curing the infection.

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AntibioticPrescription

Ciprofloxacin

Generic: Ciprofloxacin Hydrochloride

Complicated urinary tract infections, pyelonephritis, infectious bacterial diarrhea, typhoid fever, intra-abdominal infections, bone and joint infections, and anthrax post-exposure prophylaxis.

⚙️ Work Mechanism:

Ciprofloxacin halts bacterial infections by disabling the vital enzymes bacteria require to unwind, copy, and repair their genetic DNA code.

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Tetracycline AntibioticRx

Doxycycline

Generic: Doxycycline

Treat bacterial infections, acne

⚙️ Work Mechanism:

Doxycycline freezes bacterial protein synthesis by blocking amino acid delivery to bacterial ribosomes, preventing bacteria from multiplying and allowing the immune system to clear the infection.

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FluoroquinolonePrescription Only

Gatifloxacin

Generic: Gatifloxacin

Bacterial conjunctivitis

⚙️ Work Mechanism:

Gatifloxacin works at the cellular level to correct underlying biochemical imbalances, reduce clinical symptoms, and support overall health.

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AminoglycosidePrescription Only

Gentamicin

Generic: Gentamicin

Serious bacterial infections

⚙️ Work Mechanism:

Gentamicin works at the cellular level to correct underlying biochemical imbalances, reduce clinical symptoms, and support overall health.

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Urinary Anti-infectivesPrescription

Nitrofurantoin

Generic: Nitrofurantoin

Treatment and prophylaxis of urinary tract infections (UTIs)

⚙️ Work Mechanism:

Nitrofurantoin works at the cellular level to correct underlying biochemical imbalances, reduce clinical symptoms, and support overall health.

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Tetracycline AntibioticsPrescription Only

Tetracycline

Generic: Tetracycline

Treatment of various bacterial infections, acne

⚙️ Work Mechanism:

Tetracycline halts bacterial reproduction by blocking bacterial cells from manufacturing the essential proteins they require to survive.

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AminoglycosidesPrescription Only

Tobramycin

Generic: Tobramycin

Management of cystic fibrosis patients with P. aeruginosa, superficial eye infections

⚙️ Work Mechanism:

Tobramycin works at the cellular level to correct underlying biochemical imbalances, reduce clinical symptoms, and support overall health.

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