Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescription OnlyClass: Sulfonylurea

Glipizide

Generic Name: Glipizide

Common Brand Names: Glucotrol
Dosage Form:Tablet
Route:Oral
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Type 2 diabetes

Medical Conditions Treated:

Hyperglycemia

Dosage & Administration Guidelines

Adult Dosage

5 mg once daily

Pediatric Dosage

Not recommended

Elderly / Geriatric Considerations

2.5 mg once daily

Maximum Dose Limit

40 mg/day

Renal Impairment:

Use with caution

Hepatic Impairment:

Start at 2.5 mg

Side Effects & Safety Warnings

Common Side Effects

Hypoglycemia, weight gain

Serious Adverse Reactions

Severe hypoglycemia

Contraindications:

Type 1 diabetes, DKA

Important Warnings & Precautions:

Risk of hypoglycemia, especially in elderly

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Azole antifungals, NSAIDs

Food & Dietary Interactions:

Take 30 min before meals

Alcohol Interaction Warning:

Avoid, risk of disulfiram-like reaction

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Avoid

Breastfeeding / Lactation

Avoid

Patient Counseling & Practical Advice

How to Take:

Eat a meal 30 minutes after taking

What to Do if You Miss a Dose:

Do not double dose, skip if close to next meal

Recommended Monitoring & Lab Tests:

Blood glucose, HbA1c

Related Medicines in Sulfonylurea

Trustworthy Sources & Medical Review

Content for Glipizide was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.