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Unexplained Weight Loss

Educational content • Medi Info HubUpdated: 10/19/2026

Overview

Unexplained weight loss is defined as an involuntary reduction in body weight of more than 5% over a 6 to 12-month period without intentional dietary restriction or increased physical activity.

Possible Causes

Hypermetabolic endocrine states, occult neoplastic disease, malabsorption, chronic inflammatory disorders, and psychiatric conditions.

When to Seek Care

Schedule an evaluation with your physician if you have lost more than 5% of your baseline body weight unintentionally.

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.

Unexplained Weight Loss — Causes, Red Flags & When to Seek Care | Medi Info Hub | Medi Info Hub