Zyrtec
Generic Name: Cetirizine Hydrochloride
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Relief of symptoms associated with seasonal and perennial allergic rhinitis; treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.
Allergic Rhinitis, Chronic Urticaria (Hives), Allergic Conjunctivitis
Dosage & Administration Guidelines
5 mg to 10 mg orally once daily depending on symptom severity.
2.5 mg once daily for 6 months to 2 years; 2.5 mg to 5 mg for 2 to 5 years; 5 mg to 10 mg for >=6 years.
5 mg orally once daily initially due to potential renal decline.
10 mg in 24 hours.
Moderate to severe renal impairment (CrCl <=31 mL/min): 5 mg once daily.
5 mg once daily in hepatic impairment.
Side Effects & Safety Warnings
Mild somnolence, dry mouth, fatigue, pharyngitis, dizziness.
Severe hypersensitivity reactions, urinary retention.
Known hypersensitivity to cetirizine, levocetirizine, or hydroxyzine.
Caution when performing tasks requiring complete mental alertness.
Interactions (Drugs, Food & Alcohol)
CNS depressants, sedatives, alcohol.
Food does not alter overall bioavailability but may slightly delay peak absorption.
Avoid alcohol; may compound drowsiness.
Pregnancy & Breastfeeding Safety
Extensive safety record; considered one of the preferred antihistamines during pregnancy.
Excreted in breast milk; lower doses preferred to prevent infant lethargy.
Patient Counseling & Practical Advice
Although less sedating than first-generation antihistamines, it may still cause drowsiness.
Take when remembered. Do not take more than one dose in 24 hours.
Relief of allergy symptoms.
Content for Zyrtec was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.