Quetiapine
Generic Name: Quetiapine
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Schizophrenia, bipolar disorder, adjunct for major depressive disorder
Schizophrenia, Bipolar Mania, Bipolar Depression
Dosage & Administration Guidelines
50 mg daily, titrated to 300-800 mg/day based on indication
25 mg twice daily for schizophrenia (13-17 yrs)
Start at 25 mg/day, titrate slowly
800 mg/day
No adjustment necessary
Start at 25 mg/day in hepatic impairment, titrate slowly
Side Effects & Safety Warnings
Somnolence, dry mouth, dizziness, constipation, weight gain
Tardive dyskinesia, NMS, metabolic syndrome, suicidal thoughts, QT prolongation
Hypersensitivity to quetiapine
Increased mortality in elderly patients with dementia-related psychosis
Interactions (Drugs, Food & Alcohol)
CYP3A4 inhibitors/inducers, CNS depressants, QTc prolonging drugs
Take XR without food or with a light meal
Increases CNS depression
Pregnancy & Breastfeeding Safety
Risk of extrapyramidal/withdrawal symptoms in neonates
Use caution; present in human milk
Patient Counseling & Practical Advice
Take XR without food. Rise slowly to prevent dizziness. Report abnormal movements.
Take as soon as remembered. Skip if near next dose.
Lipids, fasting glucose, weight, eye exam (cataracts)
Related Medicines in Atypical Antipsychotics
Content for Quetiapine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.