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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Promethazine
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Treatment of allergic conditions, motion sickness, nausea and vomiting
Nausea/Vomiting, Motion Sickness, Allergic Rhinitis, Sedation
12.5-25 mg every 4-6 hours PRN
0.25-1 mg/kg every 4-6 hours PRN (Children >= 2 years)
Start at lower doses due to anticholinergic effects
100 mg/day
No specific adjustment required
Use with caution in hepatic impairment
Drowsiness, dry mouth, blurred vision, dizziness
Respiratory depression, extrapyramidal symptoms, neuroleptic malignant syndrome
Children < 2 years, coma, treatment of lower respiratory tract symptoms
Black box warning: Fatal respiratory depression in children < 2 years
CNS depressants, anticholinergics, MAOIs
N/A
Increases CNS depression significantly
Use if potential benefit justifies risk; avoid near term
Use caution; may inhibit lactation or cause sedation in infant
Causes extreme drowsiness. Do not drive. Avoid alcohol.
Take as soon as remembered if needed. Skip if near next dose.
Respiratory rate, mental status, anticholinergic effects
Content for Promethazine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.