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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Mirtazapine
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Treatment of major depressive disorder
Major Depressive Disorder
15 mg to 45 mg once daily at bedtime
Not FDA approved for pediatrics
Start at lower end of dosing range
45 mg/day
Consider lower doses if CrCl < 40 mL/min
Consider lower doses in hepatic impairment
Somnolence, increased appetite, weight gain, dry mouth
Agranulocytosis, serotonin syndrome, QT prolongation
Use with MAOIs
Increased risk of suicidal thinking in young adults/children
CNS depressants, SSRIs, MAOIs, CYP inducers/inhibitors
Take with or without food
Increases sedative effects
Use only if potential benefit justifies potential risk
Use caution; present in breast milk
May cause drowsiness. Report signs of infection (sore throat, fever).
Take as soon as remembered. Skip if close to next dose.
Worsening depression, suicidality, lipid profile, weight
Content for Mirtazapine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.