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Medically Verified MonographPrescription and OTCClass: Corticosteroid

Hydrocortisone

Generic Name: Hydrocortisone

Common Brand Names: Cortef, Solu-Cortef
Dosage Form:Tablet, Cream, Injection
Route:Oral, Topical, IV
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Adrenal insufficiency, inflammation, allergies

Medical Conditions Treated:

Addison's disease, severe allergic reactions, dermatitis

Dosage & Administration Guidelines

Adult Dosage

20-240 mg/day (Oral)

Pediatric Dosage

2.5-10 mg/kg/day

Elderly / Geriatric Considerations

Use with caution

Maximum Dose Limit

Varies by indication

Renal Impairment:

N/A

Hepatic Impairment:

N/A

Side Effects & Safety Warnings

Common Side Effects

Increased appetite, insomnia, skin thinning (topical)

Serious Adverse Reactions

Adrenal suppression, immunosuppression, hyperglycemia

Contraindications:

Systemic fungal infections

Important Warnings & Precautions:

Do not abruptly discontinue oral form

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

NSAIDs, antidiabetics, vaccines

Food & Dietary Interactions:

Take with food to minimize GI upset

Alcohol Interaction Warning:

May increase risk of GI ulcer

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use if benefit justifies risk

Breastfeeding / Lactation

Use with caution

Patient Counseling & Practical Advice

How to Take:

Take with meals, do not stop suddenly

What to Do if You Miss a Dose:

Take as soon as remembered

Recommended Monitoring & Lab Tests:

BP, blood glucose, bone density

Related Medicines in Corticosteroid

Trustworthy Sources & Medical Review

Content for Hydrocortisone was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.