Hydralazine
Generic Name: Hydralazine
Uses & Medical Indications
Essential hypertension
Hypertension, Heart Failure
Work Mechanism & Pharmacology
Patient Overview of Work Mechanism
Hydralazine works at the cellular level to correct underlying biochemical imbalances, reduce clinical symptoms, and support overall health.
Clinical Mechanism of Action (MoA)
Hydralazine exerts targeted therapeutic activity by interacting with specific cellular receptors, enzymatic pathways, or biological signaling cascades to relieve symptoms and restore physiological balance.
Dosage & Administration Guidelines
10-50 mg 4 times daily
0.75-3 mg/kg/day
Start low
300 mg/day
Increase dosing interval
N/A
Side Effects & Safety Warnings
Headache, tachycardia, palpitations
Lupus-like syndrome
Coronary artery disease, mitral valvular rheumatic heart disease
May cause symptomatic hypotension
Interactions (Drugs, Food & Alcohol)
MAOIs, other antihypertensives
N/A
May enhance hypotensive effect
Pregnancy & Breastfeeding Safety
Often used in pregnancy for hypertension
Compatible
Patient Counseling & Practical Advice
Take with meals, change positions slowly
Take as soon as remembered
BP, HR, ANA titer if symptoms occur
When to Seek Urgent Medical Attention
Seek immediate emergency medical care (call emergency services or proceed to the nearest emergency department) if you experience signs of a life-threatening allergic reaction (anaphylaxis: facial, lip, tongue, or throat swelling causing airway obstruction), severe cutaneous blistering with skin peeling, sudden intense chest pain, or symptoms of overdose.
Content for Hydralazine was synthesized from standardized public health monographs, official pharmacopoeias, and health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.