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Educational Medication GuideRxClass: SSRI

Citalopram

Generic Name: Citalopram

Common Brand Names: Celexa
Dosage Form:Tablet
Route:Oral
Pregnancy Category:C
Last Reviewed:9/21/2026

Uses & Medical Indications

Treat depression

Medical Conditions Treated:

Major depressive disorder

Work Mechanism & Pharmacology

How It Works

Patient Overview of Work Mechanism

Citalopram works at the cellular level to correct underlying biochemical imbalances, reduce clinical symptoms, and support overall health.

Clinical Mechanism of Action (MoA)

Citalopram exerts targeted therapeutic activity by interacting with specific cellular receptors, enzymatic pathways, or biological signaling cascades to relieve symptoms and restore physiological balance.

Primary TargetCitalopram hydrobromide
Therapeutic FamilyAntidepressant
Administration RouteOral

Dosage & Administration Guidelines

Adult Dosage

20-40 mg daily

Pediatric Dosage

Safety not established

Elderly / Geriatric Considerations

Max 20 mg daily

Maximum Dose Limit

40 mg/day

Renal Impairment:

N/A

Hepatic Impairment:

Max 20 mg daily

Side Effects & Safety Warnings

Common Side Effects

Nausea, dry mouth, insomnia

Serious Adverse Reactions

QT prolongation, serotonin syndrome

Contraindications:

Use with MAOIs or Pimozide

Important Warnings & Precautions:

Suicidal ideation in young adults

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

MAOIs, other serotonergic drugs

Food & Dietary Interactions:

N/A

Alcohol Interaction Warning:

Avoid

Identified Clinical Drug Interactions for Citalopram:

Citalopram + OndansetronMajor Interaction

Additive QT Interval Prolongation & Torsades de Pointes

Check in Tool →

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use if benefit outweighs risk

Breastfeeding / Lactation

Use caution

Patient Counseling & Practical Advice

How to Take:

May take weeks to see full effect

What to Do if You Miss a Dose:

Take as soon as remembered

Recommended Monitoring & Lab Tests:

Mood changes, ECG if at risk

Related Medicines in SSRI

Emergency Medical Warning

When to Seek Urgent Medical Attention

Seek immediate emergency medical care (call emergency services or proceed to the nearest emergency department) if you experience signs of a life-threatening allergic reaction (anaphylaxis: facial, lip, tongue, or throat swelling causing airway obstruction), severe cutaneous blistering with skin peeling, sudden intense chest pain, or symptoms of overdose.

Emergency Safety Protocol: If an intentional or accidental overdose is suspected, contact your regional Poison Control Center or emergency services immediately. Do not induce vomiting unless strictly advised by emergency healthcare personnel.
Educational Sources & References

Content for Citalopram was synthesized from standardized public health monographs, official pharmacopoeias, and health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Published by: Medi Info Hub TeamLast Updated: 10/19/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.